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ORIGINAL ARTICLE
Year : 2018  |  Volume : 52  |  Issue : 2  |  Page : 94-99

Comparison of various white spot lesion preventing medicaments: An In Vitro study


1 Prof. (Jr Grade), Department of Orthodontics and Dentofacial Orthopaedics, Faculty of Dental Sciences, KGMU, Lucknow, Uttar Pradesh, India
2 Prof., Department of Orthodontics and Dentofacial Orthopaedics, Faculty of Dental Sciences, KGMU, Lucknow, Uttar Pradesh, India
3 Professor and Head, Department of Orthodontics and Dentofacial Orthopaedics; Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, KGMU, Lucknow, Uttar Pradesh, India

Correspondence Address:
Dr. Saumya Kakkar
Room No. 202c, Buddha Hostel, KGMU, Lucknow, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jios.jios_137_17

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Objective: The objective of the study is to evaluate and compare the effectiveness of various medicaments for inhibition of enamel demineralization. Materials and Methods: A total of 125 extracted premolars were equally divided into five groups. Group 1: Control, Group 2: Fluor-Protector, Group 3: TM Plus, Group 4: Enafix, and Group 5: Amflor. Apical third of the root of bracketed teeth was sectioned off to secure teeth to the inner surface of plastic lids of 20 ml specimen jars with adhesive wax with crown immersed in Ten Cates solution. Group 1 received no further treatment; Group 2 received a single application of Flour-Protector, and Group 3, Group 4, and Group 5 received 0.5 ml applications of TM Plus, Enafix, and Amflor, respectively. Specimens were then immersed in jars containing Ten Cates solution (pH 4.3). TM Plus, Enafix, and Amflor were reapplied over Group 3, Group 4, and Group 5, every 4 hours; Group 2 received a single application of Fluor-Protector during the period of 96 h. Longitudinal sections were done; linear demineralization depth was registered using a polarized light microscope. Results: Mean enamel demineralization of groups was measured in micrometers: Control was highest, i.e., 182.98 ± 7.10, followed by Enafix i.e., 167 ± 6.00; Amflor, i.e., 165 ± 4.94; Fluor-Protector, i.e., 159.72 ± 4.62; and TM Plus, i.e.,151 ± 6.21. On comparison of groups by analysis of variance, a P = 0.004 was found. On comparison by Tukey's test, P = 0.04 between Group 1 versus 2 and P = 0.002 between Group 1 versus 3 were found, and the rest was nonsignificant. Conclusion: TM Plus was found the best among different medicaments, followed by Fluor-Protector, Amflor, and finally Enafix.


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